Name Journal of Parkinson's Disease - Impact Factor, Overall Ranking, Rating Journal Abbreviation: J PARKINSON DIS Journal ISSN: 1877-7171. Here are some critical parameters that are considered while calculating the acceptance rate: The simplest way to find out the acceptance rate or rejection rate of a Journal/Conference is to check with the journal's/conference's editorial team through emails or through the official website. The latest impact score (IS) of the Journal of Parkinson's Disease is 4.85.It is computed in the year 2022 as per its definition and based on Scopus data. The concept of 'idiopathic' Parkinson's disease (PD) as a single entity has been challenged with the identification of several clinical subtypes, pathogenic genes and putative causative environmental agents. Journal of Parkinson's Disease Wolff expressed concerns about blunt statements and the sensitive nature of the subject, and advised that only a single electronic copy be presented because it was not in Syngentas interest for multiple copies of this document to be in circulation. Authors: Bloem, Bastiaan R. | Brundin, Patrik, Article Type: tau, haplotype, mutations, variants, genome-wide association study, Citation: Journal of Parkinson's Disease, SJR is a measure of scientific influence of journals that accounts for both the number of citations received by a journal and the importance or prestige of the journals where such citations come from A common feature of implicated viruses appears to be production of high levels of cytokines and chemokines that can cross the blood-brain barrier leading to microglial activation and inflammation and ultimately neuronal cell death. Bacterial or viral infection has been proposed as a potential risk factor, and there is supporting although not entirely consistent epidemiologic and basic science evidence to support its role. The publication country of this journal is Netherlands. | Byrne, Matthew | Savica, Rodolfo | Marras, Connie, Article Type: please check the journal's official website to understand the complete publication process. While numerous independent researchers have determined that the weedkiller, paraquat, can cause neurological changes that are hallmarks of Parkinsons, Syngenta has always maintained that the evidence linking paraquat to Parkinsons disease is fragmentary and inconclusive. Berry co-authored a paper published in 2010 titled Paraquat and Parkinsons Disease in Cell Death & Differentiation, a journal owned by the Nature Portfolio, It concluded that the link between paraquat and Parkinsons was weak and evidence linking the chemical to the disease was limited and based on insufficient data. The same memorandum noted that public knowledge of Syngenta-sponsored work could have adverse consequences. Federal government websites often end in .gov or .mil. As regards symptoms and treatment, patients with Parkinsons disease on levodopa therapy and with Helicobacter pylori infection display worse motor control than those without Helicobacter infection. The purpose is to have a forum in which general doubts about the processes of publication in the journal, experiences and other issues derived from the publication of papers are resolved. On the other hand, findings of NEAT1 acting as a bona fide LRRK2 inhibitor argue for its protective role. 1 INTRODUCTION. The company had several similar relationships with outside scientists who authored papers to submit to scientific journals, the records show. There have been 1,200+ studies of paraquat and not one I repeat: not one peer-reviewed scientific publication has established a causal connection between paraquat and Parkinsons disease. Bacterial or viral infection has been proposed as a potential risk factor, and there is supporting although not entirely consistent epidemiologic and basic science evidence to support its role. The Journal of Parkinsons Disease is dedicated to providing an open forum for original research in basic science, translational research and clinical medicine that will expedite our fundamental understanding and improve treatment of Parkinsons disease. Show more, Keywords: Parkinsons disease, movement disorders, COVID-19, SARS-CoV-2, pandemic, vaccination, vaccine, efficacy, safety, adverse effects, Citation: Journal of Parkinson's Disease, vol. Get all the week's environment news - the good, the bad and the essential. The primary use of ISO 4 is to abbreviate or shorten the names of scientific journals using the technique of List of Title Word Abbreviations (LTWA). Journal of Parkinson's Disease is published by IOS Press BV. Parkinson's disease (PD) is a neurodegenerative disease with different motor and nonmotor symptoms. Front Cell Infect Microbiol. The overall rank of Journal of Parkinson's Disease is 2649. Eradication of the infection improves levodopa response in Parkinsons disease, likely as a consequence of an increased oral pre-systemic bioavailability of levodopa, likely to be explained by reduced Helicobacter-dependent levodopa consumption in the stomach. While some molecular studies suggest that mitochondrial dysfunction is a primary event in PD, others speculate that it is the result of impaired mitochondrial clearance. However, both persons with PD and physicians looking after these individuals have expressed concerns about the vaccines efficacy and safety in the specific context of PD and its symptomatic treatment. Mov Disord 34, 801811. Syngentas decision to involve lawyers in the editing of its scientific reports and other communications in ways that downplayed concerning findings potentially related to public health is unacceptable, said Wendy Wagner, a law professor at the University of Texas who has served on several National Academies of Science committees. Here, we summarize immunotherapeutic approaches that were tested in pre-clinical or clinical studies in the last two decades in an attempt to treat Parkinsons disease. Dr. Smeyne receives research support from the National Institute of Neurological Disorders and Str-oke and the National Institute of Environmental Health Science. We conduct fundamenta LCSB Luxembourg Center for Systems Biomedicine. It is published by IOS Press BV. The agency has a history of close relationships with industry, and critics say there is a revolving door of employees who move between the two, resulting in lax regulation. FOIA Journal of Parkinsons Disease Impact Factor IF 2022|2021|2020 2022 Mar 1;356:1-10. doi: 10.1016/j.toxlet.2021.12.003. Search About Journals, Conferences, and Book Series. This calls attention to the difficulties posed by the complex patho-mechanisms of neurodegenerative disorders and the limitations of disease models. Journal Abbreviation: PARKINSONS DIS-US Journal ISSN: 2090-8083. Monsanto, for example, was found to have ghostwritten scientific studies about a widely used chemical called glyphosate, the active ingredient in Monsantos Roundup herbicide. Hamadyanova AU, Kuznetsov KO, Gaifullina EI, Kalandin DA, Khamidullina RR, Khalitova IF, Faizov RM, Kamaletdinova NO, Aslanova BF, Nakieva AG, Burangulova LE, Gaisina GO. bacteria in PD risk. The implications of this for PD prevention requires attention and may be most relevant once preventive treatments for at-risk populations are developed. The h-index of Journal of Parkinson's Disease is 53. An International Standard Serial Number (ISSN) is a unique code of 8 digits. The International Standard Serial Number (ISSN) of Journal of Parkinson's Disease is/are as follows: 1877718X, 18777171. Without sufficient dopamine production, the brain is not capable of transmitting signals between cells to control movement and balance. If you need to make more complex queries, use the tips below to guide you. 2020 Mar;10(3):e01549. Considering the devastating symptoms, high prevalence, and lack of definitive diagnostic test, there is an urgent need to identify possible biomarkers and new therapeutic targets. The group, also referred to as Paraquat Communications Management Team, was to convene immediately on notification of the publication of a new study, triage the situation and plan a response, including commissioning a scientific critique. Journal Metrics | npj Parkinson's Disease - Nature Many of the documents cited in this story come from an expert report authored by David Michaels, an occupational health expert and a former top health official in both the Clinton and Obama administrations. Headquartered in Amsterdam with satellite offices in the USA, Germany and China, IOS Press continues its rapid growth, embracing new technologies for the timely dissemination of information. You are using a browser version with limited support for CSS. 2022 Mar 1;356:1-10. doi: 10.1016/j.toxlet.2021.12.003. Thus, a number of CSF and PET biomarkers beyond -synuclein, tau and A might capture these different faces of protein-related neurodegeneration. Elfil M, Kamel S, Kandil M, Koo BB, Schaefer SM. 1, pp. The best quartile for Journal of Parkinson's Disease is Q1. The ISSN is a unique 8-digit identifier for a specific publication like Magazine or Journal. A key goal was to create an international scientific consensus against the hypothesis that paraquat is a risk factor for Parkinsons disease, the documents state. Here, we discuss our perspective on. Environmental risk factors; Parkinsons disease; -synuclein. 11, no. vol. Additionally, MAPT mutations are the most common cause of familial PSP while the leucine-rich repeat kinase 2 (LRRK2 ) is a rare monogenic cause of PSP, and several other gene mutations may mimic the PSP phenotype, like the dynactin subunit 1 (DCTN1 ). Clipboard, Search History, and several other advanced features are temporarily unavailable. journal self-citations removed) received by a journal's published documents during the three previous years. The chart shows the ratio of a journal's documents signed by researchers from more than one country; that is including more than one country address. GWAS have further identified several risk loci of PSP, proposing molecular pathways related to PSP. Springer This journal has received a total of 1853 citations during the last three years (Preceding 2021). Because the benefits and risks of COVID-19 vaccines do not appear to be different than in the general population, we recommend COVID-19 vaccination with approved vaccines to persons with PD, unless there is a specific contraindication. Genes identified and/or proposed to be linked to PD encode proteins that fulfill diverse roles in cellular functions. 2022;12(8):2353-2367. doi: 10.3233/JPD-223380. 2019;9(s2):S359-S370. In 2009, Wolff went a step further, discussing legal involvement in the production of research. When it is perverted, when it is manipulated, then we get bad results. Impact of infection on risk of Parkinson's disease: a quantitative assessment of case-control and cohort studies. It is computed in the year 2022 as per its definition and based on Scopus data. The https:// ensures that you are connecting to the SJR acts as an alternative to the Journal Impact Factor (or an average number of citations received in last 2 years). Thus, in the second part of this review, we discuss therapeutic approaches targeting mitochondrial dysfunction with the aim to prevent or delay neurodegeneration in PD. The Journal of Parkinson's Disease is dedicated to providing an open forum for original research in basic science, translational research and clinical medicine that will expedite our fundamental understanding and improve treatment of Parkinson's disease. Here, we discuss our perspective on 2022 Sep 4;68(6):146-156. doi: 10.14341/probl13148. If your research field is/are related to Neurology (clinical) (Q1); Cellular and Molecular Neuroscience (Q2), then Background: Infection with Helicobacter pylori seems overrepresented in Parkinsons disease. Keywords: (modern), A tractor sprays chemicals on a field. As an open access journal, npj Parkinson's Disease . Journal of Parkinson's Disease is cited by a total of 1853 articles during the last 3 years (Preceding 2021). Careers. According to testimony given in a deposition by the top Syngenta scientist Philip Botham, and other records, Berry became a participant in Syngentas extended health science team, attending company meetings on paraquat. Regrettably, this kind of effective legal ghostwriting of scientific reports happens far too often in the chemical industry. Biological plausibility for the role for infectious agents is supported by the known neurotropic effects of specific viruses, particular vulnerability of the substantia nigra and even the promotion of aggregation of alpha-synuclein. Scimago Journal & Country Rank (SJR), https://www.scimagojr.com/, Journal Impact Factor, https://clarivate.com/. Based on multiple avenues of evidence it appears likely that specific bacterial and particularly viral infections may increase vulnerability to PD. CSF synaptic markers are attractive, still needing more evidence, which currently suggests those might be non-specific markers of disease progression. (Shrestha 2020). or intracellular alpha-synuclein could be efficient in limiting the aggregation and transmission. npj Parkinson's Disease - Impact Factor, Overall Ranking, Rating, h -. Huynh VA, Takala TM, Murros KE, Diwedi B, Saris PEJ. Wolff then became more deeply involved, records show. Not every article in a journal is considered primary research and therefore "citable", this chart shows the ratio of a journal's articles including substantial research (research articles, conference papers and reviews) in three year windows vs. those documents other than research articles, reviews and conference papers. of nuclear paraspeckles, thus regulating transcription and modifying protein functions. This journal is a member of and subscribes to the principles of the Committee on Publication Ethics. Show more, Keywords: -Synuclein, alzheimers disease, amyloid-, biomarkers, cerebrospinal fluid, lewy-type pathology, molecular imaging, Parkinsons disease, synaptic dysfunction, tau, Citation: Journal of Parkinson's Disease, Implications of the Gut Microbiome in Parkinson's Disease. Here, we summarize immunotherapeutic approaches that were tested in pre-clinical or clinical studies in the last two decades in an attempt to treat Parkinsons disease. A snippet from a Syngenta internal document regarding its Swat team, A snippet from a Syngenta internal document regarding attorney-client privilege, A snippet from a Syngenta internal document. Epidemiological evidence is most compelling for an association between PD and hepatitis C virus. Before Wang H, Liu X, Tan C, Zhou W, Jiang J, Peng W, Zhou X, Mo L, Chen L. Brain Behav. About the Journal | Journal of Parkinson's Disease It has all been turned over to lawyers who are now representing thousands of additional plaintiffs with Parkinsons disease they blame on paraquat exposure. Initially originating from the observation that mitochondrial toxins cause PD, findings from genetic PD supported a contribution of mitochondrial dysfunction to the disease. Thus, a number of CSF and PET biomarkers beyond -synuclein, tau and A might capture these different faces of protein-related neurodegeneration. Clinical Trial Highlights Parkinsons Disease Cognition, Infection and Risk of Parkinsons Disease, Mitochondria and Parkinsons Disease: Clinical, Molecular, and Translational Aspects, Treating Parkinsons Disease with Antibodies: Previous Studies and Future Directions, Genetics of Progressive Supranuclear Palsy: A Review, Neuropathological and Biomarker Findings in Parkinsons Disease and Alzheimers Disease: From Protein Aggregates to Synaptic Dysfunction. The demand or interest of researchers/scientists in publishing in a specific Journal/Conference. Arch Neurol. Those documents showed that Syngenta was aware decades ago of evidence that exposure to paraquat could impair the central nervous system, triggering tremors and other symptoms in experimental animals similar to those suffered by people with Parkinsons. Neuroscience Community - Behind the paper post, Targeted metabolomic analysis in Parkinsons disease brain frontal cortex and putamen with relation to cognitive impairment, Disruption of locus coeruleus-related functional networks in Parkinsons disease, Combining skin and olfactory -synuclein seed amplification assays (SAA)towards biomarker-driven phenotyping in synucleinopathies, Altered parabrachial nucleus nociceptive processing may underlie central pain in Parkinsons disease, Shared molecular genetic factors influence subcortical brain morphometry and Parkinsons disease risk, Postdoctoral Research Scientist in Bioinformatics and Neuroscience, PhD position Inflammation and Modifiable Risk Factors in Neurodegenerative Diseases, Postdoctoral researcher focusing on the role of molecules from the human microbiome in chronic disea. can be used for citing, indexing, abstraction, and referencing purposes. The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides. See this image and copyright information in PMC. Moreover, multiple sources of evidence suggest a cell-to-cell transmission of pathological alpha-synuclein in a prion-like manner. Journal of Parkinson's Disease has an h-index of 53. In terms of PET markers, there is no PET probe available for -synuclein yet, while the AD PET markers range from consistent evidence of their specificity (amyloid imaging) to greater uncertainty of their reliability due to off-target binding (tau imaging). Another author of the paper, Pierluigi Nicotera, scientific director and chairman of the executive board of the German Center for Neurodegenerative Diseases, said that his consultant arrangement with Syngenta ended in 2008 and he was not paid to write the 2010 article. J Neural Transm (Vienna) 105, 645676. 8600 Rockville Pike It considers the number of citations received by a journal and the importance of the journals from where these citations come. ISSN 2373-8057 (online), Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinsons disease, The genetic spectrum of a cohort of patients clinically diagnosed as Parkinsons disease in mainland China, The experience of Anxiety for people with Parkinsons disease.
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